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1

Effect of cytochrome P450 polymorphism on arachidonic acid metabolism and their impact on cardiovascular diseases

Beshay N.M. Zordoky, Ayman O.S. El-Kadi

Journal:

Pharmacology & Therapeutics

Year:

2010

Language:

english

File:

PDF, 538 KB

english, 2010

2

Sex-dependent alteration of cardiac cytochrome P450 gene expression by doxorubicin in C57Bl/6 mice

Grant, Marianne K. O., Seelig, Davis M., Sharkey, Leslie C., Zordoky, Beshay N.

Journal:

Biology of Sex Differences

Year:

2017

Language:

english

File:

PDF, 2.51 MB

english, 2017

3

Psychosocial stress unmasks latent doxorubicin-induced cardiotoxicity

Grant, Marianne, Razzoli, Maria, Bartolomucci, Alessandro, Zordoky, Beshay

Journal:

Journal of Molecular and Cellular Cardiology

Year:

2018

Language:

english

File:

PDF, 60 KB

english, 2018

4

Acute arsenic toxicity alters cytochrome P450 and soluble epoxide hydrolase and their associated arachidonic acid metabolism in C57Bl/6 mouse heart

Anwar-Mohamed, Anwar, El-Sherbeni, Ahmed A., Kim, Seok H., Althurwi, Hassan N., Zordoky, Beshay N. M., El-Kadi, Ayman O. S.

Journal:

Year:

2012

Language:

english

File:

PDF, 901 KB

english, 2012

5

Acute doxorubicin cardiotoxicity alters cardiac cytochrome P450 expression and arachidonic acid metabolism in rats

Beshay N.M. Zordoky, Anwar Anwar-Mohamed, Mona E. Aboutabl, Ayman O.S. El-Kadi

Journal:

Toxicology and Applied Pharmacology

Year:

2010

Language:

english

File:

PDF, 702 KB

english, 2010

6

Meet Our Editorial Board Member

Zordoky, Beshay N.M.

Journal:

Current Drug Metabolism

Year:

2018

Language:

english

File:

PDF, 129 KB

english, 2018

7

Soluble epoxide hydrolase inhibitor, TUPS, protects against isoprenaline-induced cardiac hypertrophy

Althurwi, Hassan N, Tse, Mandy MY, Abdelhamid, Ghada, Zordoky, Beshay NM, Hammock, Bruce D, El-Kadi, Ayman OS

Journal:

British Journal of Pharmacology

Year:

2013

Language:

english

File:

PDF, 1.27 MB

english, 2013

8

Acute arsenic treatment alters cytochrome P450 expression and arachidonic acid metabolism in lung, liver and kidney of C57Bl/6 mice

Anwar-Mohamed, Anwar, El-Sherbeni, Ahmed, Kim, Seok Hee, Elshenawy, Osama H., Althurwi, Hassan N., Zordoky, Beshay N. M., El-Kadi, Ayman O. S.

Journal:

Year:

2013

Language:

english

File:

PDF, 489 KB

english, 2013

9

Acute Doxorubicin Toxicity Differentially Alters Cytochrome P450 Expression in the Kidney and Liver of Male Sprague Dawley Rats

Beshay Zordoky, Ayman El-Kadi

Journal:

Free Radical Biology and Medicine

Year:

2010

Language:

english

File:

PDF, 379 KB

english, 2010

10

The anti-proliferative effect of metformin in triple-negative MDA-MB-231 breast cancer cells is highly dependent on glucose concentration: Implications for cancer therapy and prevention

Zordoky, Beshay N.M., Bark, Diana, Soltys, Carrie L., Sung, Miranda M., Dyck, Jason R.B.

Journal:

Biochimica et Biophysica Acta (BBA) - General Subjects

Year:

2014

Language:

english

File:

PDF, 953 KB

english, 2014

11

Response to Schoormans

Blaes, Anne, Konety, Suma, Zordoky, Beshay

Journal:

JNCI Journal of the National Cancer Institute

Year:

2020

File:

PDF, 582 KB

2020

12

Differential effects of soluble epoxide hydrolase inhibition and CYP2J2 overexpression on postischemic cardiac function in aged mice

Chaudhary, Ketul R., Zordoky, Beshay N.M., Edin, Matthew L., Alsaleh, Nasser, El-Kadi, Ayman O.S., Zeldin, Darryl C., Seubert, John M.

Journal:

Prostaglandins and Other Lipid Mediators

Year:

2013

Language:

english

File:

PDF, 1.44 MB

english, 2013

13

Molecular mechanisms and cardiovascular implications of cancer therapy-induced senescence

Abdelgawad, Ibrahim Y., Sadak, Karim T., Lone, Diana W., Dabour, Mohamed S., Niedernhofer, Laura J., Zordoky, Beshay N.

Journal:

Pharmacology & Therapeutics

Year:

2020

File:

PDF, 795 KB

2020

14

3-Methylcholanthrene and benzo(a)pyrene modulate cardiac cytochrome P450 gene expression and arachidonic acid metabolism in male Sprague Dawley rats

Mona E Aboutabl, Beshay NM Zordoky, Ayman OS El-Kadi

Journal:

British Journal of Pharmacology

Year:

2009

Language:

english

File:

PDF, 536 KB

english, 2009

15

H9c2 cell line is a valuable in vitro model to study the drug metabolizing enzymes in the heart

Beshay N.M. Zordoky, Ayman O.S. El-Kadi

Journal:

Journal of Pharmacological and Toxicological Methods

Year:

2007

Language:

english

File:

PDF, 587 KB

english, 2007

16

The interplay between genetic background and sexual dimorphism of doxorubicin-induced cardiotoxicity

Zordoky, Beshay N., Radin, M. Judith, Heller, Lois, Tobias, Anthony, Matise, Ilze, Apple, Fred S., McCune, Sylvia A., Sharkey, Leslie C.

Journal:

Cardio-Oncology

Year:

2016

Language:

english

File:

PDF, 1023 KB

english, 2016

17

2,3,7,8-Tetrachlorodibenzo-p-dioxin and β-naphthoflavone induce cellular hypertrophy in H9c2 cells by an aryl hydrocarbon receptor-dependant mechanism

Beshay N.M. Zordoky, Ayman O.S. El-Kadi

Journal:

Toxicology in Vitro

Year:

2010

Language:

english

File:

PDF, 684 KB

english, 2010

18

Resveratrol prevents hypertension and cardiac hypertrophy in hypertensive rats and mice

Dolinsky, Vernon W., Chakrabarti, Subhadeep, Pereira, Troy J., Oka, Tatsujiro, Levasseur, Jody, Beker, Donna, Zordoky, Beshay N., Morton, Jude S., Nagendran, Jeevan, Lopaschuk, Gary D., Davidge, Sandr

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease

Year:

2013

Language:

english

File:

PDF, 2.52 MB

english, 2013

19

Lack of sexual dimorphism in a mouse model of isoproterenol-induced cardiac dysfunction

Grant, Marianne K. O., Abdelgawad, Ibrahim Y., Lewis, Christine A., Seelig, Davis, Zordoky, Beshay N., Lionetti, Vincenzo

Journal:

Year:

2020

File:

PDF, 2.96 MB

2020

20

Determination of the Dominant Arachidonic Acid Cytochrome P450 Monooxygenases in Rat Heart, Lung, Kidney, and Liver: Protein Expression and Metabolite Kinetics

El-Sherbeni, Ahmed A., Aboutabl, Mona E., Zordoky, Beshay N. M., Anwar-Mohamed, Anwar, El-Kadi, Ayman O. S.

Journal:

The AAPS Journal

Year:

2013

Language:

english

File:

PDF, 341 KB

english, 2013

21

Modulation of Cardiac and Hepatic Cytochrome P450 Enzymes During Heart Failure

El-Kadi, Ayman, Zordoky, Beshay

Journal:

Current Drug Metabolism

Year:

2008

Language:

english

File:

PDF, 259 KB

english, 2008

22

Clinical and preclinical evidence of sex-related differences in anthracycline-induced cardiotoxicity

Meiners, Becky, Shenoy, Chetan, Zordoky, Beshay N.

Journal:

Biology of Sex Differences

Year:

2018

Language:

english

File:

PDF, 638 KB

english, 2018

23

Alteration of cardiac cytochrome P450-mediated arachidonic acid metabolism in response to lipopolysaccharide-induced acute systemic inflammation

Anwar Anwar-mohamed, Beshay N.M. Zordoky, Mona E. Aboutabl, Ayman O.S. El-Kadi

Journal:

Pharmacological Research

Year:

2010

Language:

english

File:

PDF, 761 KB

english, 2010

24

Inhibition of Soluble Epoxide Hydrolase Confers Cardioprotection and Prevents Cardiac Cytochrome P450 Induction by Benzo(a)pyrene

Aboutabl, Mona E, Zordoky, Beshay N M, Hammock, Bruce D, El-Kadi, Ayman O S

Journal:

Journal of Cardiovascular Pharmacology

Year:

2011

Language:

english

File:

PDF, 577 KB

english, 2011

25

Resveratrol Prevents Hypertension and Cardiac Hypertrophy in Hypertensive Rodents

Dolinsky, Vernon W., Chakrabarti, Subhadeep, Pereira, Troy J., Oka, Tatsujiro, Zordoky, Beshay N., Morton, Jude S., Nagendran, Jeevan, Opaschuk, Gary D., Davidge, Sandra T., Dyck, Jason R.B.

Journal:

Canadian Journal of Diabetes

Year:

2013

Language:

english

File:

PDF, 56 KB

english, 2013

26

Sexual dimorphism of acute doxorubicin-induced nephrotoxicity in C57Bl/6 mice

Grant, Marianne K. O., Seelig, Davis M., Sharkey, Leslie C., Choi, Wan S. V., Abdelgawad, Ibrahim Y., Zordoky, Beshay N., Mukhopadhyay, Partha

Journal:

Year:

2019

File:

PDF, 3.81 MB

2019

27

Induction of several cytochrome P450 genes by doxorubicin in H9c2 cells

Beshay N.M. Zordoky, Ayman O.S. El-Kadi

Journal:

Vascular Pharmacology

Year:

2008

Language:

english

File:

PDF, 502 KB

english, 2008

28

Role of cytochrome P450–mediated arachidonic acid metabolites in the pathogenesis of cardiac hypertrophy

Alsaad, Abdulaziz M. S., Zordoky, Beshay N. M., Tse, Mandy M. Y., El-Kadi, Ayman O. S.

Journal:

Drug Metabolism Reviews

Year:

2013

Language:

english

File:

PDF, 841 KB

english, 2013

29

Co-administration of resveratrol with doxorubicin in young mice attenuates detrimental late-occurring cardiovascular changes

Matsumura, Nobutoshi, Zordoky, Beshay N, Robertson, Ian M, Hamza, Shereen M, Parajuli, Nirmal, Soltys, Carrie-Lynn M, Beker, Donna L, Grant, Marianne K, Razzoli, Maria, Bartolomucci, Alessandro, Dyck,

Journal:

Cardiovascular Research

Year:

2018

Language:

english

File:

PDF, 775 KB

english, 2018

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